Decreased frequencies of tumor infiltrating macrophages.

<p>(A) B16F10 tumors were resected from mice at a size of 200 mm³, embedded in paraffin and stained for F4/80, as a marker for macrophages. Photos are representative for the distinct tumor areas and for more than ten analysed tumors. (B) Three tumors with comparable sizes were resected, dissociated to single cells and analysed by flow cytometry. Frequencies of myeloid subsets (from all CD11b⁺) are depicted. Frequencies of CD45⁺ infiltrating cells are depicted for CD8 T cells. Means and standard error of the mean are shown.