<p>Clinical parameters: (A) body weight, (B) grip strength, (C) paw thickness and (D) joint thickness were regularly assessed in anti-IL36R treated hTNFtg mice between 4 and 8 weeks of age. Values represent the mean ±SEM (PBS control group n = 8; treatment group n = 9).</p
INTRODUCTION: Interleukin (IL)-36 refers to three related IL-1 family cytokines, IL-36α, IL-36β, and...
<p>Arthritis score (<b>A</b>) and mean width of hind limb ankle joints (<b>B</b>). Untreated (□), PT...
<p>Suppressed incidence (A) and severity (B) of collagen induced arthritis (incomplete Freund's adju...
<p>Representative pictures and histological analyses of the hind paws of anti-IL36R and control-trea...
<p>The incidence of arthritis (A), the hind paw clinical score (B) and the hind paw thickness (C) in...
<p>(<b>A</b>) Arthritis score in mice after arthritis induction with either mannan (open circles) or...
Mean clinical severity score of mice induced with CIA demonstrating a consistent level of moderate a...
<p>Collagen induced arthritis was initiated in DBA-1 mice, subsequently treated with anti-IL-6R anti...
<p>The data are presented as arthritis score of s.c. treated CIA mice, measured from day (0) (diseas...
<p>Mice with CIA were treated with leflunomide (LEF), nimesulide (NIM), or leflunomide+nimesulide (L...
<p>Representative pictures and histomorphometry of bone parameters of trabecular bone from tibiae of...
<p>Arthritis was induced with 4mg of collagen antibodies in the WT and fat-1 mice. Clinical arthriti...
<p>WT or TSLPR-/- mice were treated with PBS or anti IL-7Rα antibodies (anti IL-7R, 100 μg ip. on da...
<p>(A) The arthritis score in CIA mice. 5–10 mice per group per experiment and data shown are repres...
<p>Clinical arthritis score during the course of <b>(A)</b> 2 weeks (WT vs. TNF<sup>ΔARE</sup>: p < ...
INTRODUCTION: Interleukin (IL)-36 refers to three related IL-1 family cytokines, IL-36α, IL-36β, and...
<p>Arthritis score (<b>A</b>) and mean width of hind limb ankle joints (<b>B</b>). Untreated (□), PT...
<p>Suppressed incidence (A) and severity (B) of collagen induced arthritis (incomplete Freund's adju...
<p>Representative pictures and histological analyses of the hind paws of anti-IL36R and control-trea...
<p>The incidence of arthritis (A), the hind paw clinical score (B) and the hind paw thickness (C) in...
<p>(<b>A</b>) Arthritis score in mice after arthritis induction with either mannan (open circles) or...
Mean clinical severity score of mice induced with CIA demonstrating a consistent level of moderate a...
<p>Collagen induced arthritis was initiated in DBA-1 mice, subsequently treated with anti-IL-6R anti...
<p>The data are presented as arthritis score of s.c. treated CIA mice, measured from day (0) (diseas...
<p>Mice with CIA were treated with leflunomide (LEF), nimesulide (NIM), or leflunomide+nimesulide (L...
<p>Representative pictures and histomorphometry of bone parameters of trabecular bone from tibiae of...
<p>Arthritis was induced with 4mg of collagen antibodies in the WT and fat-1 mice. Clinical arthriti...
<p>WT or TSLPR-/- mice were treated with PBS or anti IL-7Rα antibodies (anti IL-7R, 100 μg ip. on da...
<p>(A) The arthritis score in CIA mice. 5–10 mice per group per experiment and data shown are repres...
<p>Clinical arthritis score during the course of <b>(A)</b> 2 weeks (WT vs. TNF<sup>ΔARE</sup>: p < ...
INTRODUCTION: Interleukin (IL)-36 refers to three related IL-1 family cytokines, IL-36α, IL-36β, and...
<p>Arthritis score (<b>A</b>) and mean width of hind limb ankle joints (<b>B</b>). Untreated (□), PT...
<p>Suppressed incidence (A) and severity (B) of collagen induced arthritis (incomplete Freund's adju...