FOXP3, MHC class II, age at presentation and rescue therapy are independent prognostic factors in canine B cell lymphoma.

<p><u>Abbreviations</u>: TTR, time to remission; PFS, progression-free survival; OS, overall survival; CI, confidence interval; FOXP3⁺ (% CD5⁺CD4⁺), frequency of FOXP3⁺ cells within the sequential CD5⁺ and CD4⁺ gates; FOXP3⁺ (%), frequency of FOXP3⁺ cells within the total harvested population; median ratio = ratio of median remission or survival time (TTR/PFS/OS) of the sub-group of dogs with a value of the variable greater than the median of the group to that of the sub-group of dogs with a value of the variable less than or equal to the median of the group.