Volcano plot of Plk1-kinase-inhibited cells data.

<p>Volcano plot of the phosphoproteomic data of cells treated with an Plk1 tyrosine kinase inhibitor <i>versus</i> control <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104504#pone.0104504-Oppermann1" target="_blank">[21]</a>. Significantly regulated phosphorylation sites shown in colored circles as identified by MeanRank test, SAM, LIMMA (from left). The two rightmost volcano plots shows differences in detected phosphorylation sites by MeanRank/SAM and MeanRank/LIMMA.