m166 is crucial for <i>in vivo</i> replication of MCMV.

<p>BALB/c mice were infected with either WT (black bars) or m166^stop (gray bars) MCMV and viral pfu production was measured at d4 in (A) liver and (B) spleen. Results are representative of at least four independent experiments with four mice per group. (C) MCMV pfu production in liver at 32 h after infection with WT or m166^stop MCMV. Results are representative of two independent experiments with at least three mice per group. Dotted line denotes the limit of assay detection. Data are represented as mean +/− SEM.