Propagating wave observed after a temporary local stimulus to a bistable sheet.

<p>(<b>a</b>) Multiunit firing as recorded in the human epileptic cortex in different microelectrodes. A propagating wavefront of increased multi-unit activity can be observed. (Reprinted by permission from Macmillan Publishers Ltd: Nat. Commun. <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003787#pcbi.1003787-Schevon2" target="_blank">[54]</a>, copyright 2012.) (<b>b</b>) Cortical sheet with units that receive a pulse stimulus marked in white. Marker numbers indicate the units used for the time series in (c). (<b>c</b>) Time series of firing activity of the population for the four units marked with numbers in (b). (<b>d</b>) Snapshots of the firing activity of the population of the sheet at different time points showing a propagating wavefront of recruitment into the oscillatory state. A video of the temporal evolution is shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003787#pcbi.1003787.s029" target="_blank">Video S2</a> (compare with Supplementary Video 5 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003787#pcbi.1003787-Schevon2" target="_blank">[54]</a>). Parameter details are described in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003787#pcbi.1003787.s022" target="_blank">Text S5</a>.