<p>Available genotype calls from rare variant sanger sequencing performed on 1,998 individuals.</p> <p> </p> <p>From published paper: <em>The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals</em>. Martin Ladouceur, Zari Dastani, Yurii S. Aulchenko, Celia M. T. Greenwood, J. Brent Richards. Published online February 2nd 2012.</p> <p>DOI: 10.1371/journal.pgen.1002496</p> <p> </p
<b><i>Aims:</i></b> The study of rare variants, which can potentially explain a great proportion of ...
Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and trait...
Despite thousands of genetic loci identified to date, a large proportion of genetic variation predis...
The role of rare genetic variation in the etiology of complex disease remains unclear. However, the ...
The role of rare genetic variation in the etiology of complex disease remains unclear. However, the ...
Although genome‐wide association studies have been successful in detecting associations with common ...
A number of rare variant statistical methods have been proposed for analysis of the impending wave o...
The new class of rare variant tests has usually been evaluated assuming perfect genotype information...
There is strong evidence that rare variants are involved in complex disease etiology. The first step...
<p>Power is measured across one hundred simulations of phenotypic effects at each of 24 human gene l...
Next-generation sequencing technology allows investigation of both common and rare variants in human...
Genome-wide association studies (GWAS) have greatly improved our understanding of the genetic basis ...
A number of rare variant statistical methods have been proposed for analysis of the impending wave o...
Advances in high-throughput genomic technologies have facilitated the collection of DNA information ...
The fast development of sequencing technologies has enabled rapid and large-scale sequencing of huma...
<b><i>Aims:</i></b> The study of rare variants, which can potentially explain a great proportion of ...
Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and trait...
Despite thousands of genetic loci identified to date, a large proportion of genetic variation predis...
The role of rare genetic variation in the etiology of complex disease remains unclear. However, the ...
The role of rare genetic variation in the etiology of complex disease remains unclear. However, the ...
Although genome‐wide association studies have been successful in detecting associations with common ...
A number of rare variant statistical methods have been proposed for analysis of the impending wave o...
The new class of rare variant tests has usually been evaluated assuming perfect genotype information...
There is strong evidence that rare variants are involved in complex disease etiology. The first step...
<p>Power is measured across one hundred simulations of phenotypic effects at each of 24 human gene l...
Next-generation sequencing technology allows investigation of both common and rare variants in human...
Genome-wide association studies (GWAS) have greatly improved our understanding of the genetic basis ...
A number of rare variant statistical methods have been proposed for analysis of the impending wave o...
Advances in high-throughput genomic technologies have facilitated the collection of DNA information ...
The fast development of sequencing technologies has enabled rapid and large-scale sequencing of huma...
<b><i>Aims:</i></b> The study of rare variants, which can potentially explain a great proportion of ...
Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and trait...
Despite thousands of genetic loci identified to date, a large proportion of genetic variation predis...