<p>(A-D) Immunostaining of Smad4 in the control (A and C, <i>Tbx18<sup>Cre/+</sup>;Smad4<sup>f/+</sup></i>) and mutant ureters (B and D, <i>Smad4<sup>CKO</sup></i>) in the proximal and distal positions at E15.5. Arrowheads indicate urothelium and arrows indicate ureteral mesenchyme and SMCs.</p
<p><b>A</b>) Top panel shows H & E staining of mouse bladder anatomy from E12.5 to E16.5. <b>B</b>) ...
<p>(A–G) Transverse tissue sections of E14.5 (A–C) and E15.5 (E–G) proximal ureters showing co-immun...
<p>(A,B) Immunostaining for E-cadherin (green) and SMA (red) in <i>Sec10</i><sup><i>FL/FL</i></sup>;...
<p>(A-D) Morphology of urinary system in the control and mutant mice at E16.5 (A and B) and E18.5 (C...
Proper formation of ureteral smooth muscle cells (SMCs) during embryogenesis is essential for ureter...
<p>(A,B) GFP/RFP epifluorescence in E11.5 kidney/ureter explants of <i>Tbx18</i><sup><i>cre/+</i></s...
Proper formation of ureteral smooth muscle cells (SMCs) during embryogenesis is essential for ureter...
<p>(A, B) Apoptosis was assessed by TUNEL. Arrows indicate TUNEL positive cells. (C, D) Cell prolife...
<p>(A–F) Histological analysis was performed on newborn <i>Sec10</i><sup><i>FL/FL</i></sup>;<i>Ksp-C...
<p><b>A</b>) At E12.5, Smad4 was localized in the bladder epithelium and urethra (arrow). <b>B</b>) ...
<p><b>A</b>) At E12.5, Smad6 was localized in the bladder epithelium (arrow). <b>B</b>) At E14.5, Sm...
<p><b>A</b>) At E12.5, Smad7 was less intense and localized in the bladder epithelium (arrow). <b>B<...
<p>Embryos were collected after timed-matings to evaluate ureters at the UPJ prior to formation of t...
<p>(A-D) Morphology of whole urogenital systems of male (A,B) and female (C,D) embryos. Arrows point...
<p>All frames are fluorescence images of E17 organs stained with DAPI (blue nuclei). <b>A</b>-<b>C</...
<p><b>A</b>) Top panel shows H & E staining of mouse bladder anatomy from E12.5 to E16.5. <b>B</b>) ...
<p>(A–G) Transverse tissue sections of E14.5 (A–C) and E15.5 (E–G) proximal ureters showing co-immun...
<p>(A,B) Immunostaining for E-cadherin (green) and SMA (red) in <i>Sec10</i><sup><i>FL/FL</i></sup>;...
<p>(A-D) Morphology of urinary system in the control and mutant mice at E16.5 (A and B) and E18.5 (C...
Proper formation of ureteral smooth muscle cells (SMCs) during embryogenesis is essential for ureter...
<p>(A,B) GFP/RFP epifluorescence in E11.5 kidney/ureter explants of <i>Tbx18</i><sup><i>cre/+</i></s...
Proper formation of ureteral smooth muscle cells (SMCs) during embryogenesis is essential for ureter...
<p>(A, B) Apoptosis was assessed by TUNEL. Arrows indicate TUNEL positive cells. (C, D) Cell prolife...
<p>(A–F) Histological analysis was performed on newborn <i>Sec10</i><sup><i>FL/FL</i></sup>;<i>Ksp-C...
<p><b>A</b>) At E12.5, Smad4 was localized in the bladder epithelium and urethra (arrow). <b>B</b>) ...
<p><b>A</b>) At E12.5, Smad6 was localized in the bladder epithelium (arrow). <b>B</b>) At E14.5, Sm...
<p><b>A</b>) At E12.5, Smad7 was less intense and localized in the bladder epithelium (arrow). <b>B<...
<p>Embryos were collected after timed-matings to evaluate ureters at the UPJ prior to formation of t...
<p>(A-D) Morphology of whole urogenital systems of male (A,B) and female (C,D) embryos. Arrows point...
<p>All frames are fluorescence images of E17 organs stained with DAPI (blue nuclei). <b>A</b>-<b>C</...
<p><b>A</b>) Top panel shows H & E staining of mouse bladder anatomy from E12.5 to E16.5. <b>B</b>) ...
<p>(A–G) Transverse tissue sections of E14.5 (A–C) and E15.5 (E–G) proximal ureters showing co-immun...
<p>(A,B) Immunostaining for E-cadherin (green) and SMA (red) in <i>Sec10</i><sup><i>FL/FL</i></sup>;...