Restoration of cell-death induced inflammation by antibody-containing normal serum transfer.

<p>(A, B) The total neutrophil (A) and monocyte (B) numbers in peritoneal cavity of WT C57BL/6 mice and B lymphocyte-deficient µMT mice with or without preceding reconstitution of antibody-containing normal serum 4 hours after i.p. injection of heat-shocked necrotic EL4 cells. (C, D, E, F) The total neutrophil (C) and monocyte (D) numbers in hepatic nonparenchymal cell suspension and serum levels of ALT (E) and of total IgG (F) of mice challenged with i.p. injection of 300 mg/kg of acetaminophen in WT C57BL/6 or B lymphocyte-deficient µMT mice. The data are combined results of 4 experiments and represented as means ±SEM (<i>n</i> = total number of mice from the multiple experiments for each group). * <i>P</i><0.05, NS; not significant versus WT groups. PBS groups; WT mice received i.p. PBS.