Assessment of tumor development and progression of lung tumors in STZ-K-Ras^V12 mice compared to untreated-K-Ras^V12 ones.

<p><b>A.</b> Average number of tumors that developed per mouse in STZ-K-Ras^V12 (black bar) compared to untreated-K-Ras^V12 (white bar) mice. <b>B.</b> Average tumor size (mm²) in STZ-K-Ras^V12 (black bar) and in untreated-K-Ras^V12 mice (white bar). <b>C.</b> Expression of neoplastic tissue with the tumor burden index which considers average number of tumors per mice and average size. Data are presented as mean ± SEM, <i>*p</i><0.05 (Student's <i>t</i>-test).