Accumulation of fat in liver of leptin-deficient mice is influenced by FTO.

<p>a) Liver weight in relation to body length (n = 13, 14, 16, 14). *indicate significant p-values between <i>Lep^ob/ob;Fto^+/+</i>and <i>Lep^ob/ob;Fto^−/−</i>. b) Haematoxylin and eosin staining on paraffin sections (upper row) and oil red O staining on cryo sections (lower row) for all 4 genotypes. Scale = 100 µm. Livers were used from female mice at the age of 30 weeks. All data are presented as mean. Error bars indicate the SEM.