Changes in body weight and food intake after G-CSF or saline treatment.

<p>(A) Body weight difference from the pre-treatment body weight. Gradual decrease in body weight was shown in all animal groups, but the body weight reduction was significantly larger in G-CSF/OLETF than those in Saline/OLETF. The body weight reduction was not significantly different between G-CSF/LETO and Saline/LETO; (B) The percentage of body weight reduction in 8 weeks after the treatments was higher in G-CSF/OLETF than those in the other animal group; (C) The food intake was not significantly different between the G-CSF-treated groups and saline-treated groups of LETO and OLETF. * p<0.05 vs. saline/OLETF; † p<0.05 vs. other groups; - The data are shown as the mean ± S.E.M. G-CSF/OLETF, G-CSF-treated OLEFT; Saline/OLETF, saline-treated OLETF; G-CSF/LETO, G-CSF-treated LETO; Saline/LETO, saline-treated LETO; G-CSF, granulocyte colony-stimulating factor; OLETF, Otsuka Long-Evans Tokushima Fatty rats; LETO, Long-Evans Tokushima Otsuka rats.