Proposed model for DAP12-NKG2C complex assembly.

<p>(a), (b), and (c) are three different phases of DAP12-NKG2C complex following the unique assembly principle. The structure in (c) was obtained from our CG study, and then we converted it to an atomistic model for a better view. Polar residues Asps (red) and Thrs (pink) in DAP12 dimer and Lys (cyan) in the NKG2C TM are labeled.