Characterisation of tumour mutation status and xenograft tumours.

1<p>: p53 staining is scored as hot spots where 5 = 30–60% and 6 = 60–100%, and the staining intensity is given in brackets (1 = weak, 2 = medium and 3 = strong).</p>2<p>: S100A4 is scored as % positive cells where 1 = 1–4%, 2 = 5–9%, 3 = 10–14%, 4 = 15–49%, 5≥50%, and the staining intensities is given in brackets (1 = weak, 2 = medium and 3 = strong).</p>3<p>: Time in weeks required for the implanted patient material to reach 10 mm.</p>4<p>:Time in weeks required for the xenograft passage to reach 10 mm for F3 and forward.