a<p>The epitope used for designs. See the definition in the method.</p>b<p>Whether antigen refinement was performed.</p>c<p>K and L in the parenthesis represent KAMPA and LAMBDA light chains, respectively.</p>d<p>The Rmsd between the refined and non-refined antigen structures.</p>e<p>MILP interaction energies. Unit in kcal/mol.</p
International audienceA B‐cell epitope is the three‐dimensional structure within an antigen that can...
Therapeutic antibodies are widely used for disease detection and specific treatments. However, as an...
One third of all drugs currently in development are monoclonal antibody therapeutics. Key to the eff...
<p>(A)–(D) Model structures for epitopes of HA-all, HA-130, gp120-all and gp120–365 before (in yello...
<p>Counts of the type of amino acid mutations before (blue) and after (red) computational affinity m...
a<p>Before or after the design.</p>b<p>The counts of amino acids belonging to this classification.</...
This report represents a supplement to two recent publications in Human Immunology on the design of ...
<p>H and L chains are colored in cyan and green, respectively. Antigens are colored in orange. Hydro...
This book: Epitope Mapping covers all the major methods for the identification and definition of epi...
A important step in designing peptide vaccines involves the identification of antigenic regions in a...
<p>(i) Plots show the hydrophilicity value predicted by Hopp and Woods (blue) and antibody response ...
Comparative analysis of experimental methods of epitope mapping of protein antigens has been carried...
A) Orientations of TCRs with respect to MHCII in the 20 benchmark complexes. B) Orientations of TCRs...
Despite the high specificity between antigen and antibody binding, similar epitopes can be recognize...
Antibody arrays were developed to probe a monoclonal antibody’s three-dimensional structure (3-D str...
International audienceA B‐cell epitope is the three‐dimensional structure within an antigen that can...
Therapeutic antibodies are widely used for disease detection and specific treatments. However, as an...
One third of all drugs currently in development are monoclonal antibody therapeutics. Key to the eff...
<p>(A)–(D) Model structures for epitopes of HA-all, HA-130, gp120-all and gp120–365 before (in yello...
<p>Counts of the type of amino acid mutations before (blue) and after (red) computational affinity m...
a<p>Before or after the design.</p>b<p>The counts of amino acids belonging to this classification.</...
This report represents a supplement to two recent publications in Human Immunology on the design of ...
<p>H and L chains are colored in cyan and green, respectively. Antigens are colored in orange. Hydro...
This book: Epitope Mapping covers all the major methods for the identification and definition of epi...
A important step in designing peptide vaccines involves the identification of antigenic regions in a...
<p>(i) Plots show the hydrophilicity value predicted by Hopp and Woods (blue) and antibody response ...
Comparative analysis of experimental methods of epitope mapping of protein antigens has been carried...
A) Orientations of TCRs with respect to MHCII in the 20 benchmark complexes. B) Orientations of TCRs...
Despite the high specificity between antigen and antibody binding, similar epitopes can be recognize...
Antibody arrays were developed to probe a monoclonal antibody’s three-dimensional structure (3-D str...
International audienceA B‐cell epitope is the three‐dimensional structure within an antigen that can...
Therapeutic antibodies are widely used for disease detection and specific treatments. However, as an...
One third of all drugs currently in development are monoclonal antibody therapeutics. Key to the eff...