Counts of the type of amino acid mutations before (blue) and after (red) computational affinity maturation from the four best designed antibody models for epitopes of HA-all, HA-130, gp120-all, and gp120–365.

<p>Counts of the type of amino acid mutations before (blue) and after (red) computational affinity maturation from the four best designed antibody models for epitopes of HA-all, HA-130, gp120-all, and gp120–365.