<p>The LPS-stimulated macrophages were treated with the OWB or CA and incubated for 24 h, following which RNA was isolated for RTâPCR analysis of the expression of MyD88 (A) and TLR4 (B) mRNA. The RTâPCR data are expressed as Means ± SD from triplicate experiments. The expression of TLR4 and MyD88 was significantly higher in the LPS-induced macrophage as compared to the control and OWB or CA co-treated group (** <i>P</i></p
<p>(<b>A</b>) Macrophages were exposed to LPS (80 ng/ml) and then subjected to RIP assay using appro...
<p>HEK293 cells were transiently transfected with (A) TLR4, (B) Nod2 or (C) TLR2 and stimulated with...
<p>RNAi was used to inhibit TLR4 expression in NR8383 cells. The levels of IL-1β and TNF-α in the cu...
<p>Expression of (A) JNK, (B) MAPK, (C) IkB-α and (D) MyD88 were determined by the Western blot, us...
<p>Peritoneal macrophages were cultured overnight and incubated with LPS (1 µg/ml), washed after 4 h...
<p>A) Peritoneal macrophages from WT, conditional gp96-KO and Tlr4-KO mice were treated with LPS for...
<p>Cells were treated with LPS (1μg/mL) in the absence or presence of the constituents at different ...
<p>The macrophages in the UDCA with or without LPS group were pretreated with 1 mM UDCA for 1 h befo...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>(A, B) Peritoneal macrophages were treated with 25 μM of compound <b>1</b>. After 1 hour, compoun...
<p>Peritoneal macrophages were treated with compound <b>1</b> (25 μM) and stimulated with LPS (1 μg/...
<p><b>A. </b><i>In vitro</i> stimulation of C57BL/6 mouse spleen cells with varying doses of differe...
<p>Macrophages were incubated with medium only, LPS, or LPS in the presence of BPs. (A) Expression o...
<p>mRNA expression levels of TLR4, MyD88 and NF-kB in the inflammatory acute liver failure GalN/LPS ...
<p>Alveolar macrophages (AM) collected from WT and MyD88<sup>–/–</sup> mice were infected for 4 h wi...
<p>(<b>A</b>) Macrophages were exposed to LPS (80 ng/ml) and then subjected to RIP assay using appro...
<p>HEK293 cells were transiently transfected with (A) TLR4, (B) Nod2 or (C) TLR2 and stimulated with...
<p>RNAi was used to inhibit TLR4 expression in NR8383 cells. The levels of IL-1β and TNF-α in the cu...
<p>Expression of (A) JNK, (B) MAPK, (C) IkB-α and (D) MyD88 were determined by the Western blot, us...
<p>Peritoneal macrophages were cultured overnight and incubated with LPS (1 µg/ml), washed after 4 h...
<p>A) Peritoneal macrophages from WT, conditional gp96-KO and Tlr4-KO mice were treated with LPS for...
<p>Cells were treated with LPS (1μg/mL) in the absence or presence of the constituents at different ...
<p>The macrophages in the UDCA with or without LPS group were pretreated with 1 mM UDCA for 1 h befo...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>(A, B) Peritoneal macrophages were treated with 25 μM of compound <b>1</b>. After 1 hour, compoun...
<p>Peritoneal macrophages were treated with compound <b>1</b> (25 μM) and stimulated with LPS (1 μg/...
<p><b>A. </b><i>In vitro</i> stimulation of C57BL/6 mouse spleen cells with varying doses of differe...
<p>Macrophages were incubated with medium only, LPS, or LPS in the presence of BPs. (A) Expression o...
<p>mRNA expression levels of TLR4, MyD88 and NF-kB in the inflammatory acute liver failure GalN/LPS ...
<p>Alveolar macrophages (AM) collected from WT and MyD88<sup>–/–</sup> mice were infected for 4 h wi...
<p>(<b>A</b>) Macrophages were exposed to LPS (80 ng/ml) and then subjected to RIP assay using appro...
<p>HEK293 cells were transiently transfected with (A) TLR4, (B) Nod2 or (C) TLR2 and stimulated with...
<p>RNAi was used to inhibit TLR4 expression in NR8383 cells. The levels of IL-1β and TNF-α in the cu...