<p>Mice were treated according to the schematic shown in Fig. 5A. Mice lungs were harvested at Day 14 (prevention model) or Day 21 (therapeutic model) followed by H&E staining. Scale bar = 100 micron.</p
<p>Comparison of the lung architecture in C57Bl/6 mice after BLM instillation (21st day of the exper...
<p>The lungs (A-E) and BALF (F-I) were collected from mice on day 33 after starting saline or bleomy...
Bleomycin (BLM) induced lung injury is detectable in C57BL/6 mice using magnetic resonance imaging (...
<p>In (A) mice were treated as described in Fig. 5A followed by harvest of the right lung for a Sirc...
<p>C57Bl/6J mice had saline (n = 5 mice) or bleomycin instilled intra-tracheally (i.t.) on Day 0 and...
<p>The CSF-1 receptor inhibitor BLZ945 (200 mg/kg, open circles), vehicle (20% Captisol) (closed cir...
<div><p>A–F: MMP-13<sup>-</sup>/<sup>-</sup> and WT mice were exposed to saline (control) or bleomyc...
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatm...
Idiopathic pulmonary fibrosis (IPF) is a distressing lung disorder with poor prognosis and high mort...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
<p>(A, B) HDAC6 wild-type (WT) and knockout (KO) mice were treated with PBS or bleomycin (2units/kg;...
<p>SB525334 was administered prophylactically (<b>A</b>) or therapeutically (<b>B</b>) at a dose of ...
<p>Total collagen in the (A) skin or (B) lungs of mice challenged daily with subcutaneous bleomycin ...
(A) Chemical structure of KIRA7. (B) Schematic of the KIRA7 prevention regimen. Mice were exposed to...
Background: Pulmonary hypertension (PH) is a common complication of idiopathic pulmonary fibrosis (I...
<p>Comparison of the lung architecture in C57Bl/6 mice after BLM instillation (21st day of the exper...
<p>The lungs (A-E) and BALF (F-I) were collected from mice on day 33 after starting saline or bleomy...
Bleomycin (BLM) induced lung injury is detectable in C57BL/6 mice using magnetic resonance imaging (...
<p>In (A) mice were treated as described in Fig. 5A followed by harvest of the right lung for a Sirc...
<p>C57Bl/6J mice had saline (n = 5 mice) or bleomycin instilled intra-tracheally (i.t.) on Day 0 and...
<p>The CSF-1 receptor inhibitor BLZ945 (200 mg/kg, open circles), vehicle (20% Captisol) (closed cir...
<div><p>A–F: MMP-13<sup>-</sup>/<sup>-</sup> and WT mice were exposed to saline (control) or bleomyc...
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatm...
Idiopathic pulmonary fibrosis (IPF) is a distressing lung disorder with poor prognosis and high mort...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
<p>(A, B) HDAC6 wild-type (WT) and knockout (KO) mice were treated with PBS or bleomycin (2units/kg;...
<p>SB525334 was administered prophylactically (<b>A</b>) or therapeutically (<b>B</b>) at a dose of ...
<p>Total collagen in the (A) skin or (B) lungs of mice challenged daily with subcutaneous bleomycin ...
(A) Chemical structure of KIRA7. (B) Schematic of the KIRA7 prevention regimen. Mice were exposed to...
Background: Pulmonary hypertension (PH) is a common complication of idiopathic pulmonary fibrosis (I...
<p>Comparison of the lung architecture in C57Bl/6 mice after BLM instillation (21st day of the exper...
<p>The lungs (A-E) and BALF (F-I) were collected from mice on day 33 after starting saline or bleomy...
Bleomycin (BLM) induced lung injury is detectable in C57BL/6 mice using magnetic resonance imaging (...
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