Calculated thermodynamic activation parameters (kcal/mol) for native and mutant bovine (BT) and salmon (AST) trypsins at 300 K.

<p>*Subscripts rr, rs and ss denote, respectively, interactions among atoms in the EVB region, their interactions with the surroundings, and the internal interactions within the surroundings.</p><p>Error bars denote standard error of the mean.</p><p>Calculated thermodynamic activation parameters (kcal/mol) for native and mutant bovine (BT) and salmon (AST) trypsins at 300 K.