Parameter fit from experimental data.

<p>A: Data are reproduced from Fig. 4A in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798-BniSchnetzler1" target="_blank">[17]</a>. The function <i>g(G)</i> in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798.e004" target="_blank">Eq. (4)</a> is fitted to these data. Note <i>a</i> = 1 is used in the model, since the constant could be merged with <i>k</i>₅. B: Data were reproduced from Fig. 4B in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798-BniSchnetzler1" target="_blank">[17]</a>. The function <i>l</i>(F) in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798.e005" target="_blank">Eq. (5)</a> is fitted to these data. Note <i>a</i> = 1 is used in the model. C: Data are reproduced from Fig. 1E in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798-BniSchnetzler1" target="_blank">[17]</a>. <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798.e006" target="_blank">Eq. (6)</a> is fitted to these data. Note the interchanged axes and <i>a</i> = 1 is used in the model. D: Data are reproduced from Fig. 1C in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798-Maedler3" target="_blank">[32]</a>. The function <i>a</i>(F) in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798.e012" target="_blank">Eq. (13)</a> is fitted to these data. E: Data are reproduced from Fig. 1B in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798-Maedler3" target="_blank">[32]</a>. The function <i>p</i>(F) in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003798#pcbi.1003798.e013" target="_blank">Eq. (14)</a> is fitted to these data.