<div><p>The <i>rhl</i> quorum-sensing (QS) system plays critical roles in the pathogenesis of <i>P. aeruginosa</i>. However, the regulatory effects that occur directly upstream of the <i>rhl</i> QS system are poorly understood. Here, we show that deletion of gene encoding for the two-component sensor BfmS leads to the activation of its cognate response regulator BfmR, which in turn directly binds to the promoter and decreases the expression of the <i>rhlR</i> gene that encodes the QS regulator RhlR, causing the inhibition of the <i>rhl</i> QS system. In the absence of <i>bfmS</i>, the Acka-Pta pathway can modulate the regulatory activity of BfmR. In addition, BfmS tunes the expression of 202 genes that comprise 3.6% of the <i>P. aeruginosa<...
The opportunistic pathogen <i>Pseudomonas aeruginosa</i> uses three interwoven quorum-sensing (QS) c...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
<div><p>In <i>Pseudomonas aeruginosa</i>, the production of many secreted virulence factors is contr...
The rhl quorum-sensing (QS) system plays critical roles in the pathogenesis of P. aeruginosa. Howeve...
ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in...
Pseudomonas aeruginosa uses the two major quorum-sensing (QS) regulatory systems las and rhl to modu...
Pseudomonas aeruginosa is a prominent cystic fibrosis (CF) pathogen that uses quorum sensing (QS) to...
<div><p>In <i>Pseudomonas aeruginosa</i> quorum sensing (QS) activates the production of virulence f...
In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing...
Regulation of gene expression plays a key role in bacterial adaptability to changes in the environme...
Regulation of gene expression plays a key role in bacterial adaptability to changes in the environme...
In the opportunistic pathogen Pseudomonas aeruginosa, many virulence traits are finely regulated by ...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
In the opportunistic pathogen Pseudomonas aeruginosa, many virulence traits are finely regulated by ...
The opportunistic pathogen <i>Pseudomonas aeruginosa</i> uses three interwoven quorum-sensing (QS) c...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
<div><p>In <i>Pseudomonas aeruginosa</i>, the production of many secreted virulence factors is contr...
The rhl quorum-sensing (QS) system plays critical roles in the pathogenesis of P. aeruginosa. Howeve...
ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in...
Pseudomonas aeruginosa uses the two major quorum-sensing (QS) regulatory systems las and rhl to modu...
Pseudomonas aeruginosa is a prominent cystic fibrosis (CF) pathogen that uses quorum sensing (QS) to...
<div><p>In <i>Pseudomonas aeruginosa</i> quorum sensing (QS) activates the production of virulence f...
In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing...
Regulation of gene expression plays a key role in bacterial adaptability to changes in the environme...
Regulation of gene expression plays a key role in bacterial adaptability to changes in the environme...
In the opportunistic pathogen Pseudomonas aeruginosa, many virulence traits are finely regulated by ...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
In the opportunistic pathogen Pseudomonas aeruginosa, many virulence traits are finely regulated by ...
The opportunistic pathogen <i>Pseudomonas aeruginosa</i> uses three interwoven quorum-sensing (QS) c...
Pseudomonas aeruginosa is an opportunistic human pathogen that has the capacity to express multiple ...
<div><p>In <i>Pseudomonas aeruginosa</i>, the production of many secreted virulence factors is contr...