<p>ND- not determined.</p>a<p>Routes by which Ad was administered; iv-intravenous, ip-intraperitoneal, im-intramuscular, sq-subcutaneous.</p>b<p>Serum was collected 4 days post-treatment and VNA levels estimated by dilution ELISA for binding to toxin targets.</p><p>Serum VNA-BoNTA levels following Ad/VNA-BoNTA administration via different routes.</p
<p>Groups of five mice (60 mice in total) were treated and challenged as for study 1 (<a href="http:...
<p>(A) Lung MPO activity, (B) serum creatinine, and (C) BUN were measured 4 and 24 hours (hr) after ...
<p>Absorbance value of LAg-specific urine antibody titres in VL at day 0, before the treatment start...
<p>Mice were treated with Ad/VNA-BoNTA and intoxicated as in study 1. Here, mice were bled one week ...
<p>Serum from mice treated with Ad/VNA-BoNTA or Ad/VNA-control was collected monthly from weeks 2 th...
<p>A 10 LD<sub>50</sub> dose of BoNT/A1 was administered by intraperitoneal injection to groups of f...
<p>Groups of five mice (80 mice in total) were treated with 3×10<sup>10</sup> vp of Ad/VNA-BoNTA or ...
Current therapies for most acute toxin exposures are limited to administration of polyclonal antitox...
Current therapies for most acute toxin exposures are limited to administration of polyclonal antitox...
<p>All HFMD cases were divided into different subsets of 1, 2, 3, 4, 5 days post infection (dpi) bas...
AIMS: There are no studies measuring antivenom concentrations following intramuscular administration...
<p>(A) ALT concentration following injection with AdEasy, AdEasy-HMGA-6 or PBS as vehicle control in...
<p>(A) C<sub>max</sub> (top panel) showing expected dose-dependent increases of VRC01LS, t<sub>1/2β<...
Aims: Development of a self-sampling method for therapeutic drug monitoring (TDM) of biologicals wil...
*<p>smaller dilution not tested;</p>**<p>Patient serum was toxic for cells at a dilution <1∶5.</p><p...
<p>Groups of five mice (60 mice in total) were treated and challenged as for study 1 (<a href="http:...
<p>(A) Lung MPO activity, (B) serum creatinine, and (C) BUN were measured 4 and 24 hours (hr) after ...
<p>Absorbance value of LAg-specific urine antibody titres in VL at day 0, before the treatment start...
<p>Mice were treated with Ad/VNA-BoNTA and intoxicated as in study 1. Here, mice were bled one week ...
<p>Serum from mice treated with Ad/VNA-BoNTA or Ad/VNA-control was collected monthly from weeks 2 th...
<p>A 10 LD<sub>50</sub> dose of BoNT/A1 was administered by intraperitoneal injection to groups of f...
<p>Groups of five mice (80 mice in total) were treated with 3×10<sup>10</sup> vp of Ad/VNA-BoNTA or ...
Current therapies for most acute toxin exposures are limited to administration of polyclonal antitox...
Current therapies for most acute toxin exposures are limited to administration of polyclonal antitox...
<p>All HFMD cases were divided into different subsets of 1, 2, 3, 4, 5 days post infection (dpi) bas...
AIMS: There are no studies measuring antivenom concentrations following intramuscular administration...
<p>(A) ALT concentration following injection with AdEasy, AdEasy-HMGA-6 or PBS as vehicle control in...
<p>(A) C<sub>max</sub> (top panel) showing expected dose-dependent increases of VRC01LS, t<sub>1/2β<...
Aims: Development of a self-sampling method for therapeutic drug monitoring (TDM) of biologicals wil...
*<p>smaller dilution not tested;</p>**<p>Patient serum was toxic for cells at a dilution <1∶5.</p><p...
<p>Groups of five mice (60 mice in total) were treated and challenged as for study 1 (<a href="http:...
<p>(A) Lung MPO activity, (B) serum creatinine, and (C) BUN were measured 4 and 24 hours (hr) after ...
<p>Absorbance value of LAg-specific urine antibody titres in VL at day 0, before the treatment start...