Effect of NFA on phasic activity in intact (a–c) and denuded detrusor strips (d–f).

<p>a) A representative trace of the effect of 10 µM NFA on phasic contractions of an intact strip; bars below the trace indicate expanded regions. Effect of 3 µM, 10 µM and 30 µM NFA on b) the amplitude and c) the frequency of phasic activity in intact rat bladder strips. d) A representative trace of the effect of 30 µM NFA on phasic contractions of a denuded strip; bars below the trace indicate expanded regions. Effect of 3 µM, 10 µM and 30 µM NFA on: e) the amplitude, and f) the frequency of phasic activity in denuded rat bladder strips Baselines were pooled together for illustrative purposes. Data is presented as mean±SEM. <b>+</b> p = 0.087, * p<.05, ** p<.01, *** p<.001 vs. paired baseline phasic activity