<p>Numbers tested are in parentheses.</p><p>*p<0.05 vs WT.</p><p>Electrophysiological parameters for the wild type and p.G1911R mutant channel.</p
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>a. Currents were monitored from an oocyte expressing wild-type TRPV4 with 250 ms depolarizations ...
<p>Results obtained for different electrophysiological parameters in cells of the mNG.</p
<p>*indicates p<0.05 <i>versus</i> hNa<sub>v</sub>1.5.</p>▴<p>indicates p<0.01 <i>versus</i> hNa<sub...
Electrophysiological parameters of WT, P632L and S428P -transfected hiPSC myocytes.</p
<p>act = activation, inact = inactivation, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 as com...
<p><b>A.</b> Mean values of the variables of availability (I/I<sub>max</sub>) of WT and mutant hKv4....
<p>Electropherograms showing a wild type and the p.Arg82Leu mutation in the index patient.</p
<p>(Aa) Exemplar gating current at reversal potential (∼65 mV) for WT channels expressed with β2a. (...
<p>(A–D) Activation curves of wild type and I136V, I848T, V1316A mutant channels at 25°C (solid dots...
<p>The <i>G<sub>max</sub></i> and <i>V<sub>0.5</sub></i> of activation were determined from the <i>I...
<p>(<b>A</b>): Representative current tracings recorded in the whole cell conditions (ramp protocol ...
<p>V<sub>1/2</sub>, voltage of half-maximal (in)activation; k, slope factor of voltage- dependence o...
<p>The values of V<sub>50</sub> and k were calculated for each cell, then averaged. R values determi...
<p>Comparison of electrostatic surface potential of wild-type BglTM and N31C-T187C/P102C-N125C mutan...
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>a. Currents were monitored from an oocyte expressing wild-type TRPV4 with 250 ms depolarizations ...
<p>Results obtained for different electrophysiological parameters in cells of the mNG.</p
<p>*indicates p<0.05 <i>versus</i> hNa<sub>v</sub>1.5.</p>▴<p>indicates p<0.01 <i>versus</i> hNa<sub...
Electrophysiological parameters of WT, P632L and S428P -transfected hiPSC myocytes.</p
<p>act = activation, inact = inactivation, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 as com...
<p><b>A.</b> Mean values of the variables of availability (I/I<sub>max</sub>) of WT and mutant hKv4....
<p>Electropherograms showing a wild type and the p.Arg82Leu mutation in the index patient.</p
<p>(Aa) Exemplar gating current at reversal potential (∼65 mV) for WT channels expressed with β2a. (...
<p>(A–D) Activation curves of wild type and I136V, I848T, V1316A mutant channels at 25°C (solid dots...
<p>The <i>G<sub>max</sub></i> and <i>V<sub>0.5</sub></i> of activation were determined from the <i>I...
<p>(<b>A</b>): Representative current tracings recorded in the whole cell conditions (ramp protocol ...
<p>V<sub>1/2</sub>, voltage of half-maximal (in)activation; k, slope factor of voltage- dependence o...
<p>The values of V<sub>50</sub> and k were calculated for each cell, then averaged. R values determi...
<p>Comparison of electrostatic surface potential of wild-type BglTM and N31C-T187C/P102C-N125C mutan...
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>a. Currents were monitored from an oocyte expressing wild-type TRPV4 with 250 ms depolarizations ...
<p>Results obtained for different electrophysiological parameters in cells of the mNG.</p