Altered paired-pulse facilitation in mice lacking hippocampal and cortical primary cilia.

<p>Field recordings from CA1 hippocampus after schaffer collateral stimulation. (<b>A</b>) example traces of paired fEPSPs recorded in wild type (white) and mutant (black) hippocampal slices. (<b>B</b>) Cilia mutant neurons show an increase in paired pulse facilitation. (<b>C</b>) Long term potentiation recordings after 4 100 hz trains. Statistically significant differences are indicated: Student's t-test, * p<0.05.