<p>Numbers represent Log<sub>10</sub> genome copy numbers (GCN)/mg of tissue. FMDV RNA content in serum is expressed as Log<sub>10</sub> FMDV RNA copies/µl to facilitate comparison with viral content in tissues. Bold numbers indicate that samples were positive for both FMDV RNA (qRT-PCR) and virus isolation, (+) indicates that virus isolation was positive but FMDV RNA content was below the limit of detection, (-) indicates double negative samples. Limits of detection: tissue samples = 2.52 Log<sub>10</sub> GCN/mg, serum≤0.1 Log<sub>10</sub> GCN/µl (corresponding to an assay detection limit of 2.68 Log<sub>10</sub> GCN/ml of serum).</p><p>Tissue distribution of FMDV during viremic phase of infection following IOP inoculation.</p
<p><b>Panels A, B</b>. Cell-associated (CA)- RNA concentrations determined over the time-course in t...
Boxes along each animal’s timeline indicates a virus sample. Colors and associated Roman numerals in...
<p>BHK-21 cells were treated with AONs, or mock-treated, 3 h before infection with FMDV C-S8 at 0.1 ...
<p>Numbers represent Log<sub>10</sub> genome copy numbers (GCN)/mg of tissue. FMDV RNA content in se...
<p>Numbers represent log<sub>10</sub> FMDV genome copy numbers (GCN)/mg of tissue or GCN/μl serum. <...
<p>CB: coronary band; DSP: distal soft palate; DSP: distal nasal pharynx; IDC: interdigital cleft sk...
<p>(a) Detection of FMDV genome in mock-infected, BP15-infected, BP15.ST (anti-PPRV serum treated BP...
<p>A) Non-Vaccinated and B) Vaccinated. IFN-γ and -λ mRNA expression levels measured by qRT-PCR in m...
<p>* Sample weight calculated on basis of dissected sample volume and tissue density.</p><p>Micro-an...
a<p>10<sup>6</sup> BHK–21 cells were electroporated with 8 µg of FMDV RNA, and the amount of extrace...
<p>The presence of viral genomic RNA was determined by RT-PCR analysis in whole blood (A) and in pla...
a) The total number of nucleotide substitutions present at the consensus level at each sampled time ...
<p>Mice were infected with 1,000 SFFU of FV. (A) Cells in the BM, spleen and thymus were isolated at...
<p>2×10<sup>6</sup> BHK-21 cells were transfected with 100 ng (series <i>A</i>) (panels A, B, C) or ...
<p>Mice were infected with an inoculating dose of 1000EID<sub>50</sub> of the recombinant viruses. O...
<p><b>Panels A, B</b>. Cell-associated (CA)- RNA concentrations determined over the time-course in t...
Boxes along each animal’s timeline indicates a virus sample. Colors and associated Roman numerals in...
<p>BHK-21 cells were treated with AONs, or mock-treated, 3 h before infection with FMDV C-S8 at 0.1 ...
<p>Numbers represent Log<sub>10</sub> genome copy numbers (GCN)/mg of tissue. FMDV RNA content in se...
<p>Numbers represent log<sub>10</sub> FMDV genome copy numbers (GCN)/mg of tissue or GCN/μl serum. <...
<p>CB: coronary band; DSP: distal soft palate; DSP: distal nasal pharynx; IDC: interdigital cleft sk...
<p>(a) Detection of FMDV genome in mock-infected, BP15-infected, BP15.ST (anti-PPRV serum treated BP...
<p>A) Non-Vaccinated and B) Vaccinated. IFN-γ and -λ mRNA expression levels measured by qRT-PCR in m...
<p>* Sample weight calculated on basis of dissected sample volume and tissue density.</p><p>Micro-an...
a<p>10<sup>6</sup> BHK–21 cells were electroporated with 8 µg of FMDV RNA, and the amount of extrace...
<p>The presence of viral genomic RNA was determined by RT-PCR analysis in whole blood (A) and in pla...
a) The total number of nucleotide substitutions present at the consensus level at each sampled time ...
<p>Mice were infected with 1,000 SFFU of FV. (A) Cells in the BM, spleen and thymus were isolated at...
<p>2×10<sup>6</sup> BHK-21 cells were transfected with 100 ng (series <i>A</i>) (panels A, B, C) or ...
<p>Mice were infected with an inoculating dose of 1000EID<sub>50</sub> of the recombinant viruses. O...
<p><b>Panels A, B</b>. Cell-associated (CA)- RNA concentrations determined over the time-course in t...
Boxes along each animal’s timeline indicates a virus sample. Colors and associated Roman numerals in...
<p>BHK-21 cells were treated with AONs, or mock-treated, 3 h before infection with FMDV C-S8 at 0.1 ...