<p>(A&B) Cells were incubated with various concentrations of CCN1 (3–30 ng/ml), the OSM mRNA and protein levels rated by quantitative polymerase chain reaction (qPCR), western blot, and ELISA respectively. (C&D) Osteoblasts were incubated with CCN1 in time interval, mRNA and protein expression of OSM analyzed by qPCR, western blot, and ELISA, respectively. (E) Osteoblasts were incubated with various concentrations of CCN1 (3–30 ng/ml), the OSM luciferase activity rated by luciferase assay. (F&G) MC3T3-E1 cells were incubated with various concentrations of CCN1 (3–30 ng/ml) for 24, the OSM levels rated by western blot and ELISA. (H) Osteoblasts were incubated with CCN1 for 24 h, mRNA expression of various integrins assessed by qPCR. (I) Cell...
<p>Real–time PCR analyses of bone-associated genes expressed by MG63 osteoblast-like cells on variou...
Osteosarcoma (OS) is the most common form of malignant bone tumor and is an aggressive malignant neo...
<p>OPN (10 ng/ml) increased GLUT1 and GLUT3 protein expression in MG63 cells. This effect was signif...
<p>(A) Osteoblasts were pretreated with PDTC (10 µM) and TPCK (10 µM) or transfected with p65 siRNA ...
<p>(A) Osteoblasts were pretreated with c-Src inhibitor, PP2, or transfected with FAK siRNA followed...
Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich...
Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich...
[[abstract]]"The nephroblastoma overexpressed (NOV) gene, also called CCN3, regulates differentiati...
CCN1/Cyr61 is a dynamically expressed matricellular protein that serves regulatory functions in mult...
CYR61/CCN1 is a matricellular protein that resides in the extracellular matrix, but serves regulator...
<p><b>A (a-b)</b>: Detection of transcriptional levels of osteoblast differentiation marker genes <i...
<p>Cells were treated with cisplatin in different time or dose intervals, and the protein and mRNA e...
[[abstract]]In recent years, osteosarcoma survival rates have failed to improve significantly with c...
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play cru...
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play cru...
<p>Real–time PCR analyses of bone-associated genes expressed by MG63 osteoblast-like cells on variou...
Osteosarcoma (OS) is the most common form of malignant bone tumor and is an aggressive malignant neo...
<p>OPN (10 ng/ml) increased GLUT1 and GLUT3 protein expression in MG63 cells. This effect was signif...
<p>(A) Osteoblasts were pretreated with PDTC (10 µM) and TPCK (10 µM) or transfected with p65 siRNA ...
<p>(A) Osteoblasts were pretreated with c-Src inhibitor, PP2, or transfected with FAK siRNA followed...
Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich...
Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich...
[[abstract]]"The nephroblastoma overexpressed (NOV) gene, also called CCN3, regulates differentiati...
CCN1/Cyr61 is a dynamically expressed matricellular protein that serves regulatory functions in mult...
CYR61/CCN1 is a matricellular protein that resides in the extracellular matrix, but serves regulator...
<p><b>A (a-b)</b>: Detection of transcriptional levels of osteoblast differentiation marker genes <i...
<p>Cells were treated with cisplatin in different time or dose intervals, and the protein and mRNA e...
[[abstract]]In recent years, osteosarcoma survival rates have failed to improve significantly with c...
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play cru...
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play cru...
<p>Real–time PCR analyses of bone-associated genes expressed by MG63 osteoblast-like cells on variou...
Osteosarcoma (OS) is the most common form of malignant bone tumor and is an aggressive malignant neo...
<p>OPN (10 ng/ml) increased GLUT1 and GLUT3 protein expression in MG63 cells. This effect was signif...