Activation of γδ T cells in acute HIV infection.

<p>Activation of γδ T cells was determined by analysis of CD38 and HLA-DR expression. Frequencies of CD38+, HLA-DR+ and CD38+/HLA-DR+ γδ T cells were tested in healthy controls (HC) and acutely HIV-infected subjects at baseline (<b>A–C</b>). The patients were then subdivided based on the administration of antiretroviral therapy (ART) and CD4 levels (< or >than 350/µL). The frequencies were re-analyzed and compared with HC (<b>D–F</b>). Longitudinal follow-up of γδ T cell activation in patients with acute HIV infection was conducted at baseline, month 6 (M6), month 12 (M12) and month 18 (M18). Frequencies of CD38+, HLA-DR+ and CD38+/HLA-DR+ γδ T cells were tested in healthy controls (HC) and acutely HIV-infected subjects at baseline (<b>G–I</b>).