Histopathological findings of pulmonary inflammation.

<p>Representative results of H&E staining of lung tissue from mice in the bleomycin-induced lung injury model (A, B, C and D). H&E staining of lung tissue from (A) wild-type (WT) and (B) knockout (KO) mice on the seventh day after intratracheal administration of bleomycin. H&E staining of lung tissue from (C) WT and (D) KO mice on the 28th day after intratracheal administration of bleomycin. All scale bars = 100 µm. The window shows an area of increased magnification revealing inflammatory cell infiltration. Representative results of H&E staining of lung tissue from mice in the saline-treated control group (E, F, G and H). H&E staining of lung tissue from (E) WT and (F) KO mice on the seventh day after intratracheal administration of saline. H&E staining of lung tissue from (G) WT and (H) KO mice on the 28th day after intratracheal administration of saline. All scale bars = 100 µm. The window shows an area of increased magnification revealing hyperplasia of the alveolar/bronchiolar epithelium.