Specific activity of Pyruvate Kinase (PK)-M2 in both of human pancreatic tumor cell lines.
- Archana Pandita (627056)
- Bhupender Kumar (430944)
- Siddharth Manvati (391250)
- Samantha Vaishnavi (627057)
- Shashank K. Singh (627058)
- Rameshwar N. K. Bamezai (123255)
Publication date
September 2014
DOIAbstract
<p><i>(A) MIA PaCa-2 cells treated with Betulinic acid, Thymoquinone and Gemcitabine alone and in combination, CI<sub>(GCB:BA)</sub> and</i><i>CI<sub>(GCB:TQ)</sub> at 48 hrs. A decrease in the activity in treated cells followed with</i><i>more</i><i>decrease</i><i>in combination(s), CI<sub>(GCB:BA)</sub></i><i>and CI<sub>(GCB:TQ)</sub>,</i><i>as compared with the control was observed;</i><i>(B)</i><i>In PANC-1 cell line vice versa was observed. Control versus monotherapy (BA, TQ, GCB) and Control versus combinations (CI<sub>(GCB:BA)</sub> & CI<sub>(GCB:TQ)</sub>), (***, significant difference at p value<0.001, n = 3)</i></p
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