Voltage dependence of somatic Na⁺ channels.

<p>(A) Schematic diagram of recording from somatic nucleated patch (i.e., giant outside-out patch of somatic membrane). (B) Example current traces evoked by activation voltage commands (top) in PV and SST nucleated patches. (C) Current traces evoked by the test pulse (0 mV) in the voltage protocol for channel inactivation. (D) Comparison of averaged peak Na⁺ currents and conductance density in nucleated patches. Error bars represent s.e.m. (E and F) Activation and availability curves of somatic Na⁺ currents in PV (red) and SST neurons (blue). (Insets) Comparison of the activation and inactivation <i>V</i>_1/2, showing no difference between the two cell types. Error bars represent s.e.m.