Clinical characteristics and family history of each patient screened for <i>WFS1</i> mutations.

<p>*M, male; F, female; DM, diabetes mellitus; OA, optic atrophy; D, deafness; DI, diabetes insipidus, numbers indicate age at onset in years; +, symptomatic with unknown onset age; −, asymptomatic, Y; Yes, N; No, N/A; not applicable, □; consanguineous marriage and affected siblings.</p>§<p>Individual with detectable <i>WFS1</i> mutation in single chromosome.</p><p>Clinical characteristics and family history of each patient screened for <i>WFS1</i> mutations.