1<p>A volunteer was considered positive for an assay if activity to one or more CSP or AMA1 peptide pools was positive (see Methods). For individual protected volunteers, positive activities are in bold.</p>2<p>The number of volunteers with values higher than the highest value among the four protected DNA/Ad volunteers.</p>3<p>Highest values are for v15.</p>4<p>Two protected volunteers (v10 and v18) were lower than the highest AdCA activity.</p>5<p>p value: non-protected volunteers were included in the comparison. Statistical comparisons are included as an exploratory analysis, since the different trials were not designed or powered for a formal statistical comparison. No. = Number.</p><p>Cell mediated activities in the DNA/Ad and AdCA tr...
*<p>Window periods are shown in years for four testing algorithms for subtype A, subtype C, subtypes...
<p>Data shows percentage of CD8 cells within a CD8 gate with vaccinated as closed squares and contro...
<p>The % of cytotoxicity represents antibody-mediated cell lysis measured by release of <sup>51</sup...
<p>ELISpot, CD8+ T cell IFN-γ, and CD8+ T cell EM IFN-γ activities to individual CSP peptide pools (...
<p>Panels A and C: CD8+ T cell IFN-γ activities of each volunteer to CSP or AMA1 peptide pools are s...
<p>Panels A and C: ELISpot activities (sfc/m) of each volunteer to CSP or AMA1 peptide pools are sho...
<p>All volunteers who had positive summed and pool-specific CD8+ IFN-γ memory central (CM) and effec...
<p>The box plots (see Statistical Analysis section for description) represent anti-CSP titers and an...
<p>The box plots (see Statistical Analysis section for description) represent IFN-γ -producing CD4+ ...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
For participants with values at wk0 in the 2012/1 and wk1 in the 2007/1 study, the difference in the...
<p>A) Time course between day −1 and 7 and expression of noted markers on M1<sub>58–66</sub> tetrame...
<p>ADCC-GTL: Flow cytometric antibody-dependent cellular-cytotoxicity Gran Toxi Lux-based assay</p><...
<p>Maintenance of CD4+ T cell counts as a marker of clinical disease progression was measured by flo...
<p>Percentages of lymphocyte cell subsets CD4+ (A) and CD8+ (B) expressing CD25 for PPDB stimulated-...
*<p>Window periods are shown in years for four testing algorithms for subtype A, subtype C, subtypes...
<p>Data shows percentage of CD8 cells within a CD8 gate with vaccinated as closed squares and contro...
<p>The % of cytotoxicity represents antibody-mediated cell lysis measured by release of <sup>51</sup...
<p>ELISpot, CD8+ T cell IFN-γ, and CD8+ T cell EM IFN-γ activities to individual CSP peptide pools (...
<p>Panels A and C: CD8+ T cell IFN-γ activities of each volunteer to CSP or AMA1 peptide pools are s...
<p>Panels A and C: ELISpot activities (sfc/m) of each volunteer to CSP or AMA1 peptide pools are sho...
<p>All volunteers who had positive summed and pool-specific CD8+ IFN-γ memory central (CM) and effec...
<p>The box plots (see Statistical Analysis section for description) represent anti-CSP titers and an...
<p>The box plots (see Statistical Analysis section for description) represent IFN-γ -producing CD4+ ...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
For participants with values at wk0 in the 2012/1 and wk1 in the 2007/1 study, the difference in the...
<p>A) Time course between day −1 and 7 and expression of noted markers on M1<sub>58–66</sub> tetrame...
<p>ADCC-GTL: Flow cytometric antibody-dependent cellular-cytotoxicity Gran Toxi Lux-based assay</p><...
<p>Maintenance of CD4+ T cell counts as a marker of clinical disease progression was measured by flo...
<p>Percentages of lymphocyte cell subsets CD4+ (A) and CD8+ (B) expressing CD25 for PPDB stimulated-...
*<p>Window periods are shown in years for four testing algorithms for subtype A, subtype C, subtypes...
<p>Data shows percentage of CD8 cells within a CD8 gate with vaccinated as closed squares and contro...
<p>The % of cytotoxicity represents antibody-mediated cell lysis measured by release of <sup>51</sup...