Induction of rat acid reflux esophagitis, macroscopic, and histological findings.
- Kenichi Nakahara (629001)
- Yasuhiro Fujiwara (309173)
- Takuya Tsukahara (629002)
- Hirokazu Yamagami (482330)
- Tetsuya Tanigawa (482325)
- Masatsugu Shiba (482331)
- Kazunari Tominaga (482332)
- Toshio Watanabe (151136)
- Yoshihiro Urade (152776)
- Tetsuo Arakawa (217195)
Publication date
September 2014
DOIAbstract
<p>(A) A scheme of a rat reflux esophagitis model. (B) Macroscopic appearance of a normal esophagus. (C) Histology of the normal esophagus revealed thin epithelium with few inflammatory cells. (D) Macroscopic appearance of reflux esophagitis showed several erosions and ulcers at the middle and lower esophagus. (E) Mucosal thickening with basal cell hyperplasia and marked inflammatory cell infiltration were observed in reflux esophagitis. (Hematoxylin-eosin staining, original magnification ×200).</p
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