Changes in the AMPK pathway and its downstream key lipogenic enzymes in the liver.

<p>Mice liver samples were freeze-clamped after 4 weeks of OA administration (During OA treatment) (A) or 4 weeks after the cessation of OA administration (Post-OA treatment) (B). Liver lysates from mice were immunoblotted with phosphorylated (p-) or total (t-) AMPK, and ACC, mature form of SREBP-1c (mSREBP-1c), SCD-1, FAS and quantified for statistical analysis. Data are mean ± SE. *p<0.05 vs. T2D. n = 5–8 mice per group.