Prevalence of anti-MAP3865c antibodies in T1D and T2D patients with high-risk PDR and in healthy controls.

<p>Sera were tested for their reactivity against plate-coated MAP3865c_133–141 (A and B) and MAP3865c_125–133 (C and D) peptides. Antibody distribution is shown for T1D (A and C) and T2D (B and D) patients compared to controls. In each essay, the dotted line indicates the cut-off for positivity, as calculated by ROC analysis. The percent fraction of antibodies + sera is indicated on the top of each distribution, while bars indicate the corresponding median-interquartile range. AUC and <i>p</i> values determined by Fisher exact test are shown in the top right corner.