Induction of apoptosis by CDDO-Im in triple-negative breast cancer cells.

<p>SUM159 cells (<b>A</b>) and MDA-MB-231 cells (<b>B</b>) were incubated with vehicle control or CDDO-Im (10, 100 or 200 nM) for 24 h. The cells were stained with annexin V and propidium iodide (PI), and apoptotic cell death was determined by flow cytometry. Three separate experiments were conducted for each cell line, and representative results are shown. Averages of the three separate experiments are shown in the graph (*p<0.05, **p<0.01).