<p>The immune components selected are the area under the curve (AUC) of <b>A</b>: infected macrophages (), <b>B</b>: innate antiviral cytokines (), <b>D</b>: pro-inflammatory cytokines (), and <b>E</b>: phagocyting macrophages (); and the relative AUC of <b>C</b>: and <b>F</b>: . Two regressions were performed for each component: (i) for scenarios SBSA (dark red), in which the antiviral cytokine synthesis is higher (S0SB, red dots) or lower (S0SA, magenta dots) than in the reference scenario; (ii) for scenarios S1S2 (dark blue), in which the macrophage permissiveness is lower (S0S1, green dots) or higher (S0S2, blue dots) than in the reference scenario. Scenarios are defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journ...
<p>The figure shows the results of the linear least-squares regression analysis computed for the tra...
<p>All graphs in the figure have the same x and y axis. The label for the y axis is reported only in...
<p>(<b>A</b>) ROC curve performance of the independent variables age and NIHSSS for relative lymphoc...
<p>Evolution of twelve variables (panels <b>A</b> to <b>L</b>) during the first 30 days of infection...
<p>Scenarios S1: low macrophage permissiveness; SB: high antiviral and low immuno-modulatory cytokin...
For each simulation run we calculated the linear regression between the number of unique MHCs in ind...
<p><b>(A)</b> Scatter plot of the actual and predicted disease durations. <b>(B)</b> Scatter plot of...
<p>Experimentally determined regression equations for prediction of log(CFU) from log(qPCR) in infec...
<p>Each distinct curve represents simulations from a unique randomly obtained, physiological paramet...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
<p>Only one parameter type varies in each figure; other parameters are fixed to the values given in ...
<p>General estimating equation included to adjust for values clustered by participant. P values adju...
<p>(A) Calculation of the set-point viral load and CD4+ T-cell decline, illustrated for a single ind...
<p>A simple population genetics model predicts that absolute within-host viral adaptation rate varie...
The blue line and shadow indicate the linear regression model and the red line and shadow indicate t...
<p>The figure shows the results of the linear least-squares regression analysis computed for the tra...
<p>All graphs in the figure have the same x and y axis. The label for the y axis is reported only in...
<p>(<b>A</b>) ROC curve performance of the independent variables age and NIHSSS for relative lymphoc...
<p>Evolution of twelve variables (panels <b>A</b> to <b>L</b>) during the first 30 days of infection...
<p>Scenarios S1: low macrophage permissiveness; SB: high antiviral and low immuno-modulatory cytokin...
For each simulation run we calculated the linear regression between the number of unique MHCs in ind...
<p><b>(A)</b> Scatter plot of the actual and predicted disease durations. <b>(B)</b> Scatter plot of...
<p>Experimentally determined regression equations for prediction of log(CFU) from log(qPCR) in infec...
<p>Each distinct curve represents simulations from a unique randomly obtained, physiological paramet...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
<p>Only one parameter type varies in each figure; other parameters are fixed to the values given in ...
<p>General estimating equation included to adjust for values clustered by participant. P values adju...
<p>(A) Calculation of the set-point viral load and CD4+ T-cell decline, illustrated for a single ind...
<p>A simple population genetics model predicts that absolute within-host viral adaptation rate varie...
The blue line and shadow indicate the linear regression model and the red line and shadow indicate t...
<p>The figure shows the results of the linear least-squares regression analysis computed for the tra...
<p>All graphs in the figure have the same x and y axis. The label for the y axis is reported only in...
<p>(<b>A</b>) ROC curve performance of the independent variables age and NIHSSS for relative lymphoc...