Ectopic expression of ICP22 or the 193–256 subdomain causes loss of Ser2 phosphorylation from pol II transcribing host cell protein-coding genes.

<p>(<b>A</b>) Diagrams of the PLK2 and EIF2S3 genes, with the position of chromatin immunoprecipitation (ChIP) primer pairs indicated. (<b>B</b>), (<b>C</b>), (<b>E</b>) The results of ChIP analysis using the antibodies indicated on the left after transfection of vectors expressing the Myc-tagged proteins indicated. (<b>D</b>), (<b>F</b>) The ratio of the CTD modification to pol II as indicated at the left.