Correlation between protection, viral titers and <i>Wolbachia</i> density.

<p>Dots indicate mean value of the traits for each <i>Wolbachia</i> strain. Error bars are standard errors. Solid lines show predicted values from linear regressions for illustrative purposes. <i>r_g</i> is the genetic correlation between traits. (A) Correlation of survival between DCV- and FHV-infected flies (negative natural log of hazard ratios). (B) Correlation between DCV and FHV titers. (C–D) Correlation between viral titer and survival following (C) DCV infection or (D) FHV infection. Viral titers were estimated as viral RNA concentrations relative to the <i>Drosophila</i> gene <i>EF1α100E</i>. (E–F) Relationship between <i>Wolbachia</i> density and survival in (E) DCV- and (F) FHV-infected flies. <i>Wolbachia</i> density was estimated as the ratio between copy numbers ofthe Wolbachia gene <i>atpD</i> and the <i>Drosophila</i> gene <i>Actin 5C</i>.