VEGF overexpression cannot rescue angiogenic deficit.
- Ian M. Packham (631987)
- Steve P. Watson (74991)
- Roy Bicknell (54952)
- Stuart Egginton (74990)
Publication date
September 2014
DOIAbstract
<p>A) Extensor digitorum longus muscle VEGF expression in wildtype and MUC1-VEGF mice. MUC1-VEGF human VEGF (•) plus mouse VEGF (○) resulted in a 45% increase in total content (▪) <i>vs.</i> wildtype. B) MUC1-VEGF mice had higher initial C∶F than wildtype. Capillary sprouting with or without platelets was no different from wildtype. *<i>P</i><0.05 <i>vs.</i> C57 BL/6 controls, +<i>P</i><0.05 <i>vs.</i> contralateral.</p
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