DMH1 induces Akt activation through inhibiting PP2A in L6 cells.

<p>(<b>A</b>) DMH1 treatment showed no effect on the protein expressions of PP2A-a, PP2A-b, and PP2A-c subunits. (<b>B</b>) DMH1 treatment inhibited PP2A activity in L6 cells. **<i>P</i><0.01 vs control. (<b>C</b>) PP2A activator forskolin (40 µM) inhibited DMH1-induced Akt activation in L6 cells. **<i>P</i><0.01 <i>vs</i> control. ## <i>P</i><0.01 vs DMH1.(<b>D–E</b>) Forskolin (40 µM) showed no effects on p-AMPK level in L6 cells.