<p>Splenocytes from WT or <i>Itk</i>-KD mice were activated <i>in vitro</i> with increasing concentrations of soluble anti-CD3 for 72 h. Cell culture supernatants were collected and secreted cytokines quantified by MSD assays. Results are shown as mean +/− S.E.M. (n = 6 mice).</p
<p>Naïve CD4+ T cells from control (empty bars) or SLP76-S376A mice (filled bars) were stimulated by...
<p>Spleen cells of untreated- or 4NQO-treated wildtype or IL-23R KO mice were cultured for 3 days on...
<p>(A) IFN-γ, (B) IL-2, (C) TNF-α, (D) IL-4, (E) IL-6 and (F) IL-10. Statistical significance was de...
<p>2×10<sup>5</sup> spleen cells derived from C57BL/6 (open squares) or CD83mu (closed circles) mice...
<p>Cells were harvested from individual mice of each strain and cultured with CD3CD28 stimulation be...
<p>Splenocytes from IL-12+IL-18 mice were obtained and stained with anti-CD4, anti-CD8 and anti-CD11...
<p>Following sensitisation and challenge of mice with OVA, mediastinal lymph node cells from WT and ...
<p>Splenocytes from WT or <i>Itk</i>-KD mice were activated <i>in vitro</i> with PMA (50 ng/ml)/iono...
<p>ELIspot assays were used to detect the proliferation of antigen-specific CD4+ secreting INF-γ (<b...
<p>Three weeks after the last immunization, splenocytes were obtained from each mouse of the differe...
<p>Splenocytes from BALB/cJ mice after i.p. administration of PBS (white bars), 1 µg (gray bars) or ...
<p>Splenocytes were incubated with 5 μg/ml of LPS for 72 h. Cytokine concentrations in the supernata...
<p>(<b>A</b>) Th1 and Th2 cytokine production by splenic T cells from WT and Mst1<sup>−/−</sup> mice...
Mice were vaccinated intra-peritoneally with 108 CFU of live RB51, RB51WboA, RB51WboAKF or inoculate...
<p>Spleen cells derived from the different groups at different times were tested under the same cond...
<p>Naïve CD4+ T cells from control (empty bars) or SLP76-S376A mice (filled bars) were stimulated by...
<p>Spleen cells of untreated- or 4NQO-treated wildtype or IL-23R KO mice were cultured for 3 days on...
<p>(A) IFN-γ, (B) IL-2, (C) TNF-α, (D) IL-4, (E) IL-6 and (F) IL-10. Statistical significance was de...
<p>2×10<sup>5</sup> spleen cells derived from C57BL/6 (open squares) or CD83mu (closed circles) mice...
<p>Cells were harvested from individual mice of each strain and cultured with CD3CD28 stimulation be...
<p>Splenocytes from IL-12+IL-18 mice were obtained and stained with anti-CD4, anti-CD8 and anti-CD11...
<p>Following sensitisation and challenge of mice with OVA, mediastinal lymph node cells from WT and ...
<p>Splenocytes from WT or <i>Itk</i>-KD mice were activated <i>in vitro</i> with PMA (50 ng/ml)/iono...
<p>ELIspot assays were used to detect the proliferation of antigen-specific CD4+ secreting INF-γ (<b...
<p>Three weeks after the last immunization, splenocytes were obtained from each mouse of the differe...
<p>Splenocytes from BALB/cJ mice after i.p. administration of PBS (white bars), 1 µg (gray bars) or ...
<p>Splenocytes were incubated with 5 μg/ml of LPS for 72 h. Cytokine concentrations in the supernata...
<p>(<b>A</b>) Th1 and Th2 cytokine production by splenic T cells from WT and Mst1<sup>−/−</sup> mice...
Mice were vaccinated intra-peritoneally with 108 CFU of live RB51, RB51WboA, RB51WboAKF or inoculate...
<p>Spleen cells derived from the different groups at different times were tested under the same cond...
<p>Naïve CD4+ T cells from control (empty bars) or SLP76-S376A mice (filled bars) were stimulated by...
<p>Spleen cells of untreated- or 4NQO-treated wildtype or IL-23R KO mice were cultured for 3 days on...
<p>(A) IFN-γ, (B) IL-2, (C) TNF-α, (D) IL-4, (E) IL-6 and (F) IL-10. Statistical significance was de...