<p><u>Panel A:</u> Mouse peritoneal macrophages were transduced with AdNF-κB-Luc and treated with LPS (50 pg/ml) or Oleic acid (50 µM) as indicated. Luciferase activity was normalized to cellular protein and data are presented as percent untreated Controls (Mean ± SEM, n = 6). <u>Panel B and C:</u> Conditioned medium was collected after incubation of mouse peritoneal macrophages with LPS with or without oleic acid as indicated and IL-6 and MCP-1 levels were determined by ELISA. Data are expressed as percent of no addition control (Mean ± SEM, n = 6). P<0.0001 by One way ANOVA with Bonferroni post-hoc correction; Dissimilar letters above the bars indicate significant differences between groups (P<0.05).</p
<p>A) Absolute number of peritoneal B-1 cells (CD19<sup>+</sup>CD23<sup>−</sup>CD11b<sup>+</sup>) de...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>Macrophage-enriched spleen cell fractions of TLR4<sup>+/+</sup> (squares) and TLR4<sup>−/−</sup> ...
<p>(A) Number of peritoneal cells collected and counted individually from 6 mice (op/op<sup>(−/−)</s...
<p>RAW264.7 cells or peritoneal macrophages from BALB/c mice were treated with various concentration...
<p>(<b>A–C</b>) <i>Aoah<sup>+/+</sup></i> or <i>Aoah<sup>−/−</sup></i> mice were injected i.p. with ...
<p>After incubation with Sch A and Sch B for 6 h, RAW264.7 macrophages were challenged with LPS (1 μ...
<p>Expression of IL-1β, IL-10 and Arginase-1 in Lp-PLA<sub>2</sub> WT, HET and KO mice by RT-qPCR. D...
<p>TGC-induced peritoneal macrophages derived from B6J-WT mice (A–D) and B6N-WT and -IL-33<sup>−/−</...
<p>(A) Immunostaining analysis of LPS-induced autophagy in Rab39a-KD macrophages. Raw264.7 macrophag...
<p>(A) C57BL/6 or (B) BALB/c BMDMs were cultured in DMEM alone or in the presence of culture medium ...
<p>Peritoneal macrophages were treated with the indicated concentrations of compound <b>1</b> (2.5, ...
<p>RAW 264.7 macrophages were exposed to 1 µg/mL of LPS, during 18 h and cell viability were assesse...
<p>(A) BMDMs were pre-treated for 1 h with the indicated concentrations of AG490, BAY 11–7082, cytoc...
<p>Mice were treated with PBS or LPS (10 µg/mouse) for 3 h (Panels A–C) and 24 h (Panels D–E) and th...
<p>A) Absolute number of peritoneal B-1 cells (CD19<sup>+</sup>CD23<sup>−</sup>CD11b<sup>+</sup>) de...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>Macrophage-enriched spleen cell fractions of TLR4<sup>+/+</sup> (squares) and TLR4<sup>−/−</sup> ...
<p>(A) Number of peritoneal cells collected and counted individually from 6 mice (op/op<sup>(−/−)</s...
<p>RAW264.7 cells or peritoneal macrophages from BALB/c mice were treated with various concentration...
<p>(<b>A–C</b>) <i>Aoah<sup>+/+</sup></i> or <i>Aoah<sup>−/−</sup></i> mice were injected i.p. with ...
<p>After incubation with Sch A and Sch B for 6 h, RAW264.7 macrophages were challenged with LPS (1 μ...
<p>Expression of IL-1β, IL-10 and Arginase-1 in Lp-PLA<sub>2</sub> WT, HET and KO mice by RT-qPCR. D...
<p>TGC-induced peritoneal macrophages derived from B6J-WT mice (A–D) and B6N-WT and -IL-33<sup>−/−</...
<p>(A) Immunostaining analysis of LPS-induced autophagy in Rab39a-KD macrophages. Raw264.7 macrophag...
<p>(A) C57BL/6 or (B) BALB/c BMDMs were cultured in DMEM alone or in the presence of culture medium ...
<p>Peritoneal macrophages were treated with the indicated concentrations of compound <b>1</b> (2.5, ...
<p>RAW 264.7 macrophages were exposed to 1 µg/mL of LPS, during 18 h and cell viability were assesse...
<p>(A) BMDMs were pre-treated for 1 h with the indicated concentrations of AG490, BAY 11–7082, cytoc...
<p>Mice were treated with PBS or LPS (10 µg/mouse) for 3 h (Panels A–C) and 24 h (Panels D–E) and th...
<p>A) Absolute number of peritoneal B-1 cells (CD19<sup>+</sup>CD23<sup>−</sup>CD11b<sup>+</sup>) de...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>Macrophage-enriched spleen cell fractions of TLR4<sup>+/+</sup> (squares) and TLR4<sup>−/−</sup> ...