<p>Associations are reported between anti-MSP1<sub>19</sub> or anti-AMA1 total IgG ELISA titer readouts between two allelic variants of each antigen – ETSR (3D7) and QKNG (K1/Wellcome) for MSP1<sub>19</sub>, and 3D7 and FVO for AMA1. Responses were assessed following vaccination only, vaccination + CHMI, CHMI only (control volunteers) and in naturally-exposed Kenyan adults (as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107903#pone-0107903-g001" target="_blank">Figure 1B, D</a>). In all cases, Spearman’s rank correlation coefficient and <i>P</i> value are shown. n.d. = not done (too few positive responders). *Relevant data were pooled for analysis from vaccinees receiving either a single vaccine or co...
<p>(A) Anti-MSP1<sub>19</sub> responses in the VAC037 Phase Ia clinical trial (open symbols) <a href...
<p>(<b>A</b>) Groups 1A and 2A and (<b>B</b>) groups 1B and 2B total IgG ELISA responses against 3D7...
<p>The box plots (see Statistical Analysis section for description) represent anti-CSP titers and an...
<p>Serum IgG1 and IgG3 isotype responses were assessed by ELISA against (A) MSP119 (ETSR allele) and...
<p>Associations are reported between anti-MSP1<sub>19</sub> ETSR allele or anti-AMA1 3D7 allele tota...
<p>Isotype profiles of serum antibody responses were assessed by ELISA. (A) Individual and median an...
<p>Associations are reported between anti-MSP1<sub>19</sub> or anti-AMA1 total IgG ELISA titer reado...
<p>Mean anti-MSP1<sub>19</sub> serum IgG responses were assessed over time by ELISA in a Phase IIa C...
<p>Antibodies to recombinant AMA1 protein were tested by standard ELISA. Antibodies to specific AMA1...
Background RTS,S/AS01 induced anti-circumsporozoite protein (CSP) IgG antibodies are associated w...
<p>Correlation between singleplex and multiplex assays for AMA1 allele-specific antibodies.</p
Introduction: Identifying immune correlates of protection is a priority for malaria vaccine research...
Although Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candida...
Although Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candida...
Background The ability to report vaccine-induced IgG responses in terms of µg/mL, as opposed arbitra...
<p>(A) Anti-MSP1<sub>19</sub> responses in the VAC037 Phase Ia clinical trial (open symbols) <a href...
<p>(<b>A</b>) Groups 1A and 2A and (<b>B</b>) groups 1B and 2B total IgG ELISA responses against 3D7...
<p>The box plots (see Statistical Analysis section for description) represent anti-CSP titers and an...
<p>Serum IgG1 and IgG3 isotype responses were assessed by ELISA against (A) MSP119 (ETSR allele) and...
<p>Associations are reported between anti-MSP1<sub>19</sub> ETSR allele or anti-AMA1 3D7 allele tota...
<p>Isotype profiles of serum antibody responses were assessed by ELISA. (A) Individual and median an...
<p>Associations are reported between anti-MSP1<sub>19</sub> or anti-AMA1 total IgG ELISA titer reado...
<p>Mean anti-MSP1<sub>19</sub> serum IgG responses were assessed over time by ELISA in a Phase IIa C...
<p>Antibodies to recombinant AMA1 protein were tested by standard ELISA. Antibodies to specific AMA1...
Background RTS,S/AS01 induced anti-circumsporozoite protein (CSP) IgG antibodies are associated w...
<p>Correlation between singleplex and multiplex assays for AMA1 allele-specific antibodies.</p
Introduction: Identifying immune correlates of protection is a priority for malaria vaccine research...
Although Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candida...
Although Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candida...
Background The ability to report vaccine-induced IgG responses in terms of µg/mL, as opposed arbitra...
<p>(A) Anti-MSP1<sub>19</sub> responses in the VAC037 Phase Ia clinical trial (open symbols) <a href...
<p>(<b>A</b>) Groups 1A and 2A and (<b>B</b>) groups 1B and 2B total IgG ELISA responses against 3D7...
<p>The box plots (see Statistical Analysis section for description) represent anti-CSP titers and an...