Ketogenic diets reduced serum glucose concentration and enhanced metformin effects on reducing 4T1 breast tumor growth in Balb/c mice.

<p><b>A.</b> Serum glucose was measured and demonstrated as bar graph. Data are presented as mean ± standard deviation. Groups on Ketogenic diets are significant different from groups on control diets. <b>B.</b> Tumor growth was measured at indicated time for CD (control diet), CD+Met (control diet plus metformin), KD (ketogenic diet) and KD+Met (ketogenic diet plus metformin). CD+Met treatment group was significantly different from KD+Met treatment group after day 11. <b>C.</b> Tumor volume at day 23. Data are presented as mean ± standard deviation (**indicates significant difference between groups).