<p>Activity scores from an NIH HTS screening of five isozymes of cytochrome P450 against 17K compounds, merged with the 2-D descriptors of those compounds as generated by the program Molecular Opreating Environment. Datasets are separated by isozyme.</p
Semi-automated high throughput screening for the inhibition of major human cytochrome P450 enzymes (...
The cytochrome P450 isoenzymes are a super family of haemoproteins that are terminal oxidases of mix...
In mammals, Cytochrome P450 (CYP) enzymes are bound to membranes of the endoplasmic reticulum and mi...
The cytochrome P450 (CYP) gene family strongly influences drug development. We determined potency va...
Cytochromes P450 (CYP) are a superfamily of enzymes, involved in metabolism of xenobiotic compounds....
Activities of recombinant human cytochrome P450 isoforms towards compounds 1a and 2a.</p
Includes bibliographical references.Cytochrome P450 (CYPs) are a superfamily of heme containing enzy...
<p>Taken from pubchem - results of HTS of 17000 compounds against 5 isozymes of Cytochrome P450.</p
NoCytochrome P450 (CYP) is one of the most important drug-metabolizing enzyme families, which partic...
International audienceCytochromes P450 (CYPs) are a superfamily of 57 genes coding for drug metaboli...
A unified proteochemometric (PCM) model for the prediction of the ability of drug-like chemicals to ...
Dmitrij A Sychev,1 Ghulam Md Ashraf,2 Andrey A Svistunov,3 Maksim L Maksimov,4 Vadim V Tarasov,3 Vla...
The potential for metabolism-related drug-drug interactions by new chemical entities is assessed by ...
A unified proteochemometric (PCM) model for the prediction of the ability of drug-like chemicals to ...
h aIntroduction The P450 cytochromes (CYP) are a superfamily of enzymes found in the liver which cat...
Semi-automated high throughput screening for the inhibition of major human cytochrome P450 enzymes (...
The cytochrome P450 isoenzymes are a super family of haemoproteins that are terminal oxidases of mix...
In mammals, Cytochrome P450 (CYP) enzymes are bound to membranes of the endoplasmic reticulum and mi...
The cytochrome P450 (CYP) gene family strongly influences drug development. We determined potency va...
Cytochromes P450 (CYP) are a superfamily of enzymes, involved in metabolism of xenobiotic compounds....
Activities of recombinant human cytochrome P450 isoforms towards compounds 1a and 2a.</p
Includes bibliographical references.Cytochrome P450 (CYPs) are a superfamily of heme containing enzy...
<p>Taken from pubchem - results of HTS of 17000 compounds against 5 isozymes of Cytochrome P450.</p
NoCytochrome P450 (CYP) is one of the most important drug-metabolizing enzyme families, which partic...
International audienceCytochromes P450 (CYPs) are a superfamily of 57 genes coding for drug metaboli...
A unified proteochemometric (PCM) model for the prediction of the ability of drug-like chemicals to ...
Dmitrij A Sychev,1 Ghulam Md Ashraf,2 Andrey A Svistunov,3 Maksim L Maksimov,4 Vadim V Tarasov,3 Vla...
The potential for metabolism-related drug-drug interactions by new chemical entities is assessed by ...
A unified proteochemometric (PCM) model for the prediction of the ability of drug-like chemicals to ...
h aIntroduction The P450 cytochromes (CYP) are a superfamily of enzymes found in the liver which cat...
Semi-automated high throughput screening for the inhibition of major human cytochrome P450 enzymes (...
The cytochrome P450 isoenzymes are a super family of haemoproteins that are terminal oxidases of mix...
In mammals, Cytochrome P450 (CYP) enzymes are bound to membranes of the endoplasmic reticulum and mi...
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