Fecal ash copper contents and changes of body weight of the transgenic and control mice.

<p>At 4 wk of age, all G1 offspring were weaned and fed with the prepared feed (copper content, 10 mg/kg). Subsequently, the fecal samples were collected and the body weights of the mice were recorded once daily for 2 wk. (A) The fecal copper contents of the mice were analyzed. The fecal ash copper contents of transgenic mice (n = 28) were significantly lower than the control mice (n = 16), presenting a reduction of 18.41% (*<i>P</i> = 0.0022<0.01) and 21.61% (*<i>P</i> = 0.0003<0.01) for the first week and the second week, respectively. (B) The changes of body weight of the mice were analyzed. After 1 and 2 wk, the body-weight of transgenic mice (n = 28) increased significantly (*<i>P</i> = 0.025<0.05; *<i>P</i> = 0.019<0.05, respectively) compared with those of the control mice (n = 16) at 7.2% and 12.97%, respectively. 1st: the first; 2nd: the second.