Representative immunohistochemical pictures of (A) TRPA1 and (B) TRPV1 labelling of intact, non-inflamed distal colon sections of C57Bl/6 mice drinking water or inflamed tissues of mice receiving dextran-sulphate (DSS) for 7 days.

<p>Insert: KP1 (anti-CD68) antibody-labelled macrophages. Asterix: colon lumen. Arrows: <i>a:</i> weak immunopositivity on mucosal epithelial cells; <i>b:</i> remarkable immunopositivity around mucosal nerves and blood vessels; <i>c:</i> myenteric plexus nerve fibers; <i>d:</i> myenteric plexus ganglia; <i>e</i>: submucous plexus. <i>g:</i> infiltrating immune cells; <i>h:</i> marked immunopositivity on inflammatory leukocytes. <i>i:</i> interstitial plasma cells in the submucosa.