Response to ATP (A) and oscillatory fluid flow (B) was decreased in P2Y₂ KO mice.

<p>(Left: western blot analysis of ERK1/2 phosphorylation in primary osteoblastic cells. Right: Bar graph representation of ERK1/2 phosphorylation quantified by scanning densitometry normalized to total ERK1/2). (n = 4–6, *p<0.05) Each bar represents SEM.